Want to get this tested? Gamma GT. What does the test result mean? A low or normal GGT test result indicates that it is unlikely that a person has liver disease.
Book a free demo. Small amounts are present in other tissues. Even though renal tissue has the highest level of GGT, the enzyme present in the serum appears to originate primarily from the hepatobiliary system, and GGT activity is elevated in any and all forms of liver disease.
It is highest in cases of intra- or posthepatic biliary obstruction, reaching levels some 5 to 30 times normal. GGT is more sensitive than alkaline phosphatase ALP , leucine aminopeptidase, aspartate transaminase, and alanine aminotransferase in detecting obstructive jaundice, cholangitis, and cholecystitis; its rise occurs earlier than with these other enzymes and persists longer. Only modest elevations times normal occur in infectious hepatitis, and in this condition, GGT determinations are less useful diagnostically than are measurements of the transaminases.
High elevations of GGT are also observed in patients with either primary or secondary metastatic neoplasms. Elevated levels of GGT are noted not only in the sera of patients with alcoholic cirrhosis but also in the majority of sera from persons who are heavy drinkers. Studies have emphasized the value of serum GGT levels in detecting alcohol-induced liver disease. The results can't show which condition you have, but it can help show how much liver damage you have. Usually, the higher the level of GGT, the greater the level of damage to the liver.
If your results show you have low or normal levels of GGT, it means you probably don't have liver disease. Your results may also be compared with the results of an ALP test. ALP tests help diagnose bone disorders. Together your results may show one of the following:. Learn more about laboratory tests, reference ranges, and understanding results. These include:. The information on this site should not be used as a substitute for professional medical care or advice.
Contact a health care provider if you have questions about your health. What is a gamma-glutamyl transferase GGT test? What is it used for? A GGT test is most often used to: Help diagnose liver disease Figure out if liver damage is due to liver disease or a bone disorder Check for blockages in the bile ducts Screen for or monitor alcohol use disorder. Afterward, there may be some throbbing or a slight bruise. This soon goes away. GGT is an enzyme found in high level in the liver, kidney, pancreas, heart, and brain.
It is also found in lesser amount in other tissues. An enzyme is a protein that causes a specific chemical change in the body. This test is used to detect diseases of the liver or bile ducts. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results.
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